The patient’s increasingly early menstruation at the age of 40 may be a manifestation of perimenopause, or it may be caused by endocrine disorders, adenomyosis, uterine fibroids and other factors. Patients are advised to go to the hospital for treatment in a timely manner to clarify the cause and treat the cause: 1. Perimenopause: With the decline of ovarian function, the level of estrogen and progesterone decreases, which can be manifested as a gradual shortening of the menstrual cycle and a decrease in menstrual volume, accompanied by anxiety, Menopause is a normal natural phenomenon, patients in daily life through regular exercise, balanced diet, quit smoking, limit alcohol, keep a happy spirit to alleviate symptoms, and pay attention to prevent osteoporosis, avoid fractures; 2, endocrine disorders: patients due to mental factors or environmental changes lead to endocrine disorders, will appear more and more early menstruation performance, patients should promptly go to the hospital to check the level of sex hormones and thyroid hormones. After the cause is clear, you can use kunlin pills, ethinyl estradiol cyproterone tablets, etc. to regulate endocrine secretion and relieve symptoms; 3, adenomyosis: If patients suffer from adenomyosis, due to the invasion of endometrial glands and mesenchyme into the myometrium, and maintain periodic exfoliation, will lead to the symptoms of early menstruation, patients should go to the hospital in a timely manner, under the guidance of doctors to carry out drug conservative treatment or adenomyomectomy, endometrial resection and other surgical procedures. If the patient has submucosal fibroids or large interstitial fibroids protruding into the mucosal layer, it will lead to shortened menstrual cycle, early menstruation, or even prolonged menstruation and increased menstrual volume. Surgery is recommended for larger fibroids with abnormal menstruation or severe anemia. 5. Endometrial lesions: endometrial hyperplasia, endometrial polyps, etc. can also cause menstrual cycle disorders and early menstruation, which can be treated with medication or surgery under the guidance of a doctor.