A tooth that hurts badly at night is, in most cases, a case of pulpitis. In this case, the best way is to go to the dentist and have the pulp drained, and the pain will be relieved immediately. However, if you do not have the conditions to seek immediate medical attention, you can only take drugs, which are generally analgesic drugs, because the effect of anti-inflammatory drugs is relatively slow. These drugs have relatively good analgesic effects, while the side effects are not particularly large, and can be used as the first line of common analgesic drugs.