Drinking headache may be due to alcohol stimulation of nerves, vasoconstriction caused by insufficient cerebral blood supply or alcohol poisoning and other reasons, the patient can take non-steroidal anti-inflammatory drugs, vasodilator drugs or to promote the metabolism of alcohol drugs and other treatments according to the different situations. 1. non-steroidal anti-inflammatory drugs: due to alcohol stimulation of the nerve caused by the headache, you can take non-steroidal anti-inflammatory drugs for treatment, commonly used drugs such as ibuprofen, etc., through the inhibition of the synthesis of prostaglandins, play an analgesic effect. 2. vasodilator drugs: some patients with headaches after drinking, may also be due to vasoconstriction caused by insufficient blood supply to the brain, you can take flunarizine and other vasodilator drugs for treatment. Through the expansion of blood vessels, relieve vascular spasm, increase the blood supply to the brain, so as to relieve the symptoms of headache. 3. Alcohol metabolism drugs: If the headache is caused by alcoholism, you can take Metadoxine and other alcohol metabolism drugs for treatment, which can promote the metabolism of ethanol, and can be used to alleviate the headache caused by alcoholism. If you have a headache after drinking, you should go to the hospital in time for examination, and take medication under the guidance of the doctor, to avoid unauthorized use of drugs on the body to cause serious harm.