The choice of antipyretic strategy is not particularly influential in the case of fever with low back pain; whether or not the fever is reduced should depend on the degree of the fever and the severity of the accompanying symptoms. If the back pain is particularly pronounced, antipyretic drugs can also be taken specifically for this reason. If there is no significant vomiting, oral preparations of ibuprofen and acetaminophen can be given. If there is recurrent vomiting, you can opt for rectal medication in the form of indomethacin suppositories for adults and acetaminophen suppositories for children. It is also important to look for changes in back pain after the fever has subsided. If back pain is subsequently relieved, the problem is usually not serious. In some cases, it is edema of the kidneys as well as acute lesions that cause low back pain, which then also needs to be combined with urine routine and kidney ultrasound to determine if the kidney function is damaged. If it is hemorrhagic fever nephrotic syndrome, you can also choose to apply glucocorticoids to control systemic inflammation, which also have the effect of assisting in reducing fever after application.