The patient is a 38-year-old male with a 10-year history of ankylosing spondylitis and has had limited lumbar activity for the past 5 years. 2 years ago, he accidentally sprained his back, resulting in intractable low back pain, which was severe when standing and sitting up, and significantly limited his quality of life. 1 year ago, he was seen at several hospitals, including Jishuitan Hospital and Union Hospital, where he was considered to have a suspected fracture of the lumbar spine and was given conservative treatment such as strict bed rest and oral painkillers, but did not see significant relief. In the past 6 months, the patient was bedridden at home due to recurrent lumbar pain, and severe lumbar pain occurred when he turned over. The patient was referred to the orthopedic department of our hospital, and Director Tang Hai considered the patient to have ankylosing spondylitis combined with L2 and L3 vertebral body fractures. On 7-2, the operation went smoothly, and the traditional commercial bone cement was mixed with artificial bone repair material and injected into the diseased vertebrae through the working cannula. The patient’s pain was significantly relieved after the operation, and he could turn over in bed after 6 h. He could sit up at the bedside and stand for a short time with a lumbar support 24 h after the operation. After regular functional exercise of the lumbar and back muscles, the patient can now walk a little on his own on the 5th postoperative day, and his quality of life has improved significantly.