Patients with significant allergy to cold air that occurs by chance can apply antihistamines such as loratadine, cetirizine, paracetamol, etc. for oral administration. Usually, the allergic inflammatory reaction can be effectively relieved after about 3-5 days of application. If the patient is repeatedly allergic to cold air, a special type of urticaria should be considered, which is cold-irritant urticaria. In this case, the patient can apply antihistamines intermittently in the usual way, or apply traditional Chinese medicine to regulate. However, the application of these drugs can only provide short-term relief. If patients want to avoid this skin allergy, the most important thing is to strengthen the local skin warmth, minimize the cold air on the skin stimulation, in order to minimize the occurrence of this skin allergy.