Uric acid in the body is usually formed by the breakdown and metabolism of purines.
The sources of uric acid in the human body include the breakdown of nucleotides in food, accounting for about 20% of the total uric acid in the body. The main pathway of human purine synthesis can generate uric acid, through the body’s amino phosphate ribose and other small molecule compounds synthesized or nucleic acid decomposition and other processes, the production of uric acid accounts for about 80% of the total uric acid. Uric acid is mainly excreted in the form of free monosodium urate by the kidneys through the urine.
Changes in blood uric acid levels are affected by diet, medication, disease, and other factors, and persistent high or low levels are usually abnormal, and should be promptly consulted to determine the cause.
If the patient has abnormal changes in blood uric acid level, it is recommended to consult the Rheumatology Department of the hospital in a timely manner.