Heartburn refers to a burning sensation or pain in the area of the heart within the chest cavity, also known as heartburn. It may be due to gastroesophageal reflux disease (GERD), angina pectoris, etc. It can be treated symptomatically with medication or surgery. 1. Gastroesophageal Reflux Disease (GERD): Stomach acid enters the esophagus and irritates the mucosal epithelium, causing pain, heartburn, acid reflux, coughing and other symptoms. The treatment of GERD is mainly based on medication, including gastric acid inhibiting drugs such as omeprazole, gastric power drugs such as domperidone, mucosal protective agents such as bismuth pectin, and antibiotics such as clarithromycin if combined with Helicobacter pylori infection. In severe cases, surgical anti-reflux treatment is needed. 2. Angina: some angina pectoris in the attack in addition to the typical anterior region of the heart pain squeezing feeling, choking feeling, may also appear local burning sensation. Sublingual nitroglycerin can be used to relieve acute pain, and calcium blockers such as nifedipine, beta-blockers such as atenolol, and anti-myocardial ischemic drugs such as trimetazidine can be used on a daily basis, and interventional stenting is required for severe cases. The above drugs should be used under the guidance of clinicians, and unauthorized use of medication is prohibited; symptoms such as heartburn, acid reflux, chest pain, etc., it is recommended to go to the hospital in a timely manner and treat according to the doctor’s instructions to avoid delays in the condition.