Skin peeling and bleeding in the middle of the penis may be related to friction injury, fungal dermatitis, atopic dermatitis, etc., and needs to be judged in conjunction with a specific medical history. 1. Friction injury: Penile peeling and bleeding may be caused by clothing friction, friction during sex, etc., resulting in skin injury, usually with a clear history of dry friction. Iodine can be used to disinfect, pay attention to cleanliness and hygiene. You can also take cephalosporin and levofloxacin prophylactically under the guidance of a doctor to prevent infection. 2. Fungal dermatitis: fungal infection, resulting in ringworm and other lesions, can trigger penile skin itching, scratching due to uncontrollable, resulting in penile skin ulceration, resulting in penile peeling and bleeding phenomenon. This condition is usually accompanied by obvious itching symptoms. You can use econazole, tretinoin, ketoconazole cream externally as prescribed by the doctor. It can also be combined with oral medication. 3. Allergic dermatitis: drug allergy, underwear allergy, or condom allergy, etc., can lead to penile skin allergy, itching, scratching the middle of the penis peeling and bleeding. First of all, you should remove the allergens, disinfect with iodophor alcohol, apply appropriate topical medication, or use anti-allergic drugs such as cetirizine and loratadine. After the penis peeling skin bleeding, we should immediately seek medical treatment, active examination, according to the results of the examination to confirm the diagnosis, follow the doctor’s prescription of symptomatic medication.