The skull is one of the hard bones in the body and plays an important role in protecting the brain tissue inside the skull and maintaining the intracranial environment. If an accident occurs that results in a cranial defect, then a cranial repair should be performed promptly. In theory, as long as the brain tissue in the defective area is not affected, skull repair can be left alone. In practice, however, there is simply no way to ensure that the brain tissue in the damaged part is in a normal, healthy state. Without the protection of brain tissue by the skull, even without the stimulation of external conditions, the human body’s own scalp and hair will spread, contact and cover the brain tissue directly, and the brain tissue will be displaced with the change of body position for a long time, causing the change of blood circulation in the brain, or due to the adhesive displacement of the scalp and dura mater, the subarachnoid space disappears, the cerebral cortex perfusion decreases, and the softening foci of brain tissue under the bone window increase, which can form traumatic cysts , cerebral penetration malformation, ventricular asymmetry, etc. The direct manifestation is the patient’s headache and dizziness, fear of sun and noise, and not only psychological shadows such as low self-esteem and depression, but also may cause memory loss and poor concentration. Therefore, skull repair is performed not only for the aesthetics of the patient’s head, but also for the health of the patient’s life. At present, we use PEEK cranial bone repair, using bionic materials with high affinity to human bones, three-dimensional reconstruction to highly restore the structure of the skull, so that the damaged area and the original bone window fit beautifully, not only the appearance is identical, but also can accelerate the development of bone healing, is worthy of the patient’s better repair material.