Ketoconazole lotion and selenium disulfide are two different drugs, often used to treat dandruff, seborrheic dermatitis and other problems. However, there are differences in the applicability and adverse reactions of these two drugs, which cannot be compared, and there is no good or bad, so you need to choose a more suitable drug to relieve the discomfort according to your own situation under the guidance of your doctor. 1, ketoconazole lotion: ketoconazole is a broad-spectrum antifungal drug, if the patient has more dandruff, seborrheic dermatitis, accompanied by fungal infection and scalp itching, you can choose ketoconazole lotion , the efficacy is better. However, it should be noted that a few patients will have allergic reactions after use, with redness and itchiness of the scalp, and some patients also have hair breakage and hair loss after use. In addition, the use of ketoconazole lotion immediately after the long-term use of corticosteroids may also appear to stimulate the scalp, resulting in itchy scalp and other uncomfortable symptoms, attention can be paid to avoid the situation; 2, selenium disulfide: If the patient has too much dandruff, oil secretion caused by seborrheic dermatitis of the scalp, you can choose selenium disulfide lotion. Selenium disulfide has a certain anti-seborrhea, antifungal effect, so the treatment of seborrheic dermatitis effect will be better. It is worth noting that selenium disulfide may cause contact dermatitis as well as hair discoloration, etc. The drug also has some toxicity and is forbidden to be taken internally as well as applied to the external genital area. In addition, both can be used for the treatment of ringworm and lichen planus. Patients who experience adverse reactions such as itchy scalp when using either of the above two drugs, or if the symptoms are not relieved or even worsened, should go to the hospital and take the relevant treatment under the guidance of a doctor.