Omeprazole enteric-coated tablets and Xiaojianzhong Granules can theoretically be taken together, but whether they need to be taken at the same time or not needs to be used according to the condition under the guidance of a doctor. 1. Omeprazole enteric-coated tablets is a proton pump inhibitor, can inhibit gastric acid secretion, after the use of the drug on the heartburn and pain relief faster, the cure rate of duodenal ulcers is also higher, and the recurrence rate is lower. It can be used to treat gastric ulcer, duodenal ulcer, reflux esophagitis, gastrinoma and so on. Adverse reactions are small, mainly headache, dry mouth, nausea and so on. It is prohibited for those who are allergic to the product, those with severe renal insufficiency and infants. 2. Xiao Jianzhong Granules is a kind of Chinese patent medicine, which has the efficacy of warming the middle and tonifying the deficiency, easing the urgency and relieving the pain (relieving the more urgent pain symptoms), with small toxic side effects. It can be used for spleen and stomach deficiency (spleen and stomach weakness and cold), epigastric (abdominal) pain, like warmth and like to press, noisy acid swallowing (discomfort in the stomach, acid on the flood and then swallowed), less food palpitations (heartbeat, often accompanied by panic) and diarrhea and constipation alternating with the symptoms of chronic colitis, gastric and duodenal ulcers. Not recommended for pregnant women. It is not suitable for patients with external wind-heat syndrome and patients with damp-heat in the spleen and stomach (spleen and stomach feeling damp-heat evil) or obvious gastrointestinal bleeding symptoms. Clinically these two drugs can be taken together without obvious interaction. However, whether it is necessary to take at the same time, need to be under the guidance of a doctor.