If a 50-year-old woman has very little menstrual flow and still has very little menstrual flow after taking progesterone, she is considered to have entered perimenopause, and she can follow the trend of ovarian decline without having to continue to take medication to force her to have menstrual flow. Women enter perimenopause around the age of 49, which is a normal physiological phenomenon. At this time, for perimenopausal women will have low menstrual flow, delayed menstrual cycle, shortened menstrual period, or laxity of menstrual flow, and other signs of ovarian decline. Progesterone is a progestin, one of the hormones secreted by the ovaries. Some women take progesterone or other medications to regulate perimenopausal menstrual disorders in an attempt to lengthen the menstrual period, increase menstrual flow, and improve the quality of life, but these hormone medications also have the side effects of increasing the risk of liver and kidney damage, blood clots, and stimulating the risk of tumors in the reproductive system. On balance, it is advisable to go along with the process of ovarian decline and not to force medication to improve menstrual flow.