Uterine fibroids are common benign tumors of the female genitalia, and their occurrence is related to the level of female sex hormones, and they tend to occur in women of reproductive age. After menopause, fibroids can partially atrophy or recede, which is related to the degree of decline in hormone levels in the body after menopause, as well as the number and size of fibroids. The estrogen conversion of estradiol in fibroids is significantly lower than in normal muscle tissue, and the concentration of estrogen receptors is significantly higher than in the surrounding muscle tissue, so it is believed that the local hypersensitivity of fibroid tissue to estrogen is an important factor in its occurrence, while progesterone plays a role in promoting fibroid mitosis and stimulating fibroid growth. The faster and higher the level of hormones in a woman’s body decreases after menopause, the greater the rate and degree of atrophy of the fibroids, so it is possible for some women to have their fibroids recede, or at least shrink in size. For small fibroids, during the postmenopausal decline of estrogen and progesterone, the fibroids lose enough hormonal support and shrink completely. In the case of smaller fibroids, they may have more estrogen and progesterone stored in themselves, so even if the hormone level in the body decreases, the fibroids have corresponding hormonal support, so they will not completely recede, but the size will generally be smaller than the original. In conclusion, whether the fibroids can be completely receded or not is related to the decline of hormone level, the number and size of fibroids, and cannot be completely determined, so it is better to monitor their size regularly.