Pepsinogen ratio less than 3 may be caused by improper diet, atrophic gastritis, chronic gastritis, etc. It can be relieved by improving diet, medication and surgery. 1. Improper diet: Pepsinogen ratio less than 3 can occur easily if stomach irritation is caused by eating spicy and stimulating food. You can improve your diet by keeping it light, avoiding stimulating foods, and consuming foods that promote gastric acid secretion such as kiwi, lemon, and honey. 2. Atrophic gastritis: Atrophic gastritis caused by Helicobacter pylori infection or excessive smoking and alcohol abuse is prone to have a pepsinogen ratio of less than three. It can be relieved by avoiding sharing utensils and cups, avoiding mouth-to-mouth feeding, avoiding spoiled food, developing good work and rest habits, or taking medications such as omeprazole enteric-coated capsules, mosapride tablets, ranitidine tablets, and so on. 3. Chronic gastritis: If bile reflux, bacterial infection and other causes of gastric mucosa repeated damage caused by chronic gastritis, easy to appear pepsinogen ratio of less than 3. You can choose domperidone tablets, aluminum sulfate tablets, pancreatic enzyme tablets and other drugs to improve, or with gastroscopy submucosal dissection and other methods to improve. Drugs need to be used according to the doctor’s prescription, if the ratio is consistently low, you need to consult a doctor in time.