Women in the early stage of pregnancy will have some clinical symptoms such as menopause, early pregnancy reaction, frequent urination and breast changes due to the change of hormone level in the body and the enlargement of the uterus pressing on the pelvic organs; there are light and heavy symptoms depending on the age, physical quality and work pressure of individuals. 1.Menopause is the earliest symptom of first pregnancy. For women of childbearing age who have normal sex life, pregnancy should be highly suspected once menstruation reaches more than 10 days (10 days of menopause). 2, women after pregnancy due to changes in the body hormone levels can appear early pregnancy reaction, such as cold, dizziness, limb weakness, drowsiness, nausea and vomiting, hate greasy, like to eat sour food, etc., mostly in about 6 weeks after menopause, about 12 weeks disappear on their own; because of the different physical qualities of individuals, the reaction can be light or heavy, the light ones can be relieved after paying attention to diet and rest; the heavy ones need to go to the hospital for rehydration and conditioning, such as severe pregnancy vomiting. The reaction of nausea and vomiting is heavy, resulting in the inability to eat and water, disorder of electrolytes (mainly K ions) in the body, increase of ketone bodies, and in serious cases, miscarriage or maternal ketoacidosis. In the early stage of pregnancy, the enlarged uterus presses on the bladder in front of the pelvic cavity, causing the pregnant mother to urinate frequently. As the pregnancy lengthens, the enlarged uterus gradually enters the abdominal cavity and the symptoms of frequent urination gradually disappear. 4.Pregnant women can feel breast swelling and pain, breast volume gradually becomes bigger, nipple areola enlarges, coloring deepens, Montserrat nodules (dark brown nodules around areola) can appear, gynecological examination sexual duplex examination can appear black plus sign (uterine isthmus is extremely soft, feeling that the cervix is not connected with the uterine body). Clinically, since the symptoms of appeal in the early stages of pregnancy are usually not obvious, doctors mainly rely on auxiliary investigations to clarify pregnancy and the time of pregnancy: such as qualitative and quantitative determination of blood HCG, vaginal ultrasound view, etc.