The common cause of hand numbness and hand pain caused by exertion is the long-term overuse of the wrist to produce wrist nerve strain, such as the elbow median nerve, ulnar nerve, etc. At this time, you can apply hot compresses, massage to relieve the pain, you can also take medication, and the serious need for surgical treatment. Hand numbness and hand pain caused by exertion can be relieved by physical therapy, such as hot compresses, local massage of the painful parts to promote blood circulation and improve the symptoms of hand numbness and hand pain. Commonly used drugs for hand numbness and hand pain caused by exertion are non-steroidal anti-inflammatory and analgesic drugs, such as aspirin, ibuprofen, and sodium lorzolophine. These drugs have anti-inflammatory and analgesic effects. Nutritional nerve drugs can also be used, such as methylcobalamin, vitamin B6 and so on. Hand numbness and pain caused by exertion can be treated surgically if it is not relieved by medication. For example, carpal tunnel syndrome is usually treated with traditional open carpal tunnel decompression and endoscopic carpal tunnel release decompression. It is important to note that when taking medication for hand numbness and hand pain caused by exertion, you should follow your doctor’s advice, and if your symptoms are not relieved for a long time, you should follow your doctor’s advice for further treatment.