Moles, also known as pigmented nevi, are removed mainly by non-surgical and surgical methods. Surgical removal is recommended for soybean-sized moles. Soybean-sized moles are not suitable for laser removal. Laser treatment cannot completely remove pigmented moles and is prone to scarring; multiple treatments increase the stimulation of the mole cells, which may lead to the risk of malignant changes. For soybean-sized moles, the clinic mostly chooses to treat them through surgical excision. Especially for moles in friction areas such as hands and feet, the probability of malignant transformation is relatively high, so it is recommended to perform surgical excision and send the excised part for pathological examination. Do not scratch or apply corrosive agents to remove moles, so as not to irritate the skin and cause local infections. Patients who wish to get rid of moles are recommended to go to a specialized hospital for consultation, conduct relevant examinations, and then follow the doctor’s instructions to choose the appropriate way to get rid of moles and carry out the treatment.