Nucleic acid testing is recommended 48 hours after the New Crown vaccine. It is generally recommended that nucleic acid testing be performed after 48 hours after the New Crown vaccination. The results of nucleic acid testing are generally not affected after vaccination with the New Crown vaccine. However, because of the possibility of exposure to fragments of viral nucleic acid during the vaccination process, which can lead to false-positive nucleic acid tests, it is necessary to perform nucleic acid testing 48 hours after vaccination. Currently, the common nucleic acid test mainly utilizes PCR technology to amplify the unique nucleic acid fragments of the neocoronavirus in the sample to determine the presence or absence of infection, which is the primary criterion for confirming the diagnosis of neocoronavirus infection. The neocoronavirus vaccine is primarily an inactivated viral vaccine, which is non-infectious and non-pathogenic, and produces protective antibodies that do not lead to neocoronavirus infection after vaccination. However, there is a relatively complete nucleic acid fragment of the virus in the vaccine, and during the vaccination process, the vaccinee may carry some of the vaccine liquid and other substances, and immediate nucleic acid testing may lead to false positives. Therefore, it is generally recommended that nucleic acid testing be performed 48 hours after vaccination to avoid false positives.