Hepatitis A, Hepatitis B and Hepatitis C can be differentiated by pathogens, prognosis, means of transmission and treatment methods. 1. Different prognosis: Hepatitis A has no chronic type, only acute hepatitis A; part of acute hepatitis B will become chronic hepatitis B, and some patients may cause cirrhosis or even liver cancer; part of acute hepatitis C will be transformed into chronic hepatitis C. 2. Different pathogens: the pathogen of hepatitis A is hepatitis A virus; the pathogen of hepatitis B is hepatitis B virus; the pathogen of hepatitis C is hepatitis C virus. 3. Different ways of transmission: Hepatitis A is transmitted through the digestive tract; Hepatitis B is transmitted through sexual contact, blood, body fluids, and mother-to-child transmission; Hepatitis C is transmitted in a way similar to that of Hepatitis B. 4. Treatment: Hepatitis A has the tendency of self-cure, and the seriousness of the disease needs to be treated according to individual differences. Hepatitis B is generally based on the control of viral replication, there is no specific drug; Hepatitis C can be treated with small molecule drugs and can be cured. In addition, hepatitis A, hepatitis B and hepatitis C are all harmful, and patients are advised to accept the examination and treatment actively.