Darvon is a near-natural progestin and progesterone is an all-natural progestin, both of which can be used to protect the fetus and regulate menstruation. Daphne has very mild side effects, with few side effects, and is more effective than progesterone. Progesterone, if taken orally, can cause dizziness, nausea, vomiting and drowsiness in some people; Duffetone does not have these adverse effects. Therefore, these two drugs are generally better than Duffetone, from the treatment effect and side effects are much better than progesterone, but, the price of Duffetone is higher than progesterone.