Damage to the kidneys from levofloxacin is relatively rare, but may lead to abnormal kidney function or even acute renal failure. Medication should be used in accordance with medical advice. Levofloxacin is a common anti-infective drug, which may produce multi-system side effects after administration. According to the drug test and clinical experience, the proportion of kidney damage is relatively rare, but it may cause abnormal renal function or even acute renal failure. If patients have renal insufficiency, levofloxacin should be used with caution, and the dose of the drug should be adjusted if needed. In addition, Levofloxacin may cause tendonitis, hepatotoxicity, QT interval prolongation, central nervous system reactions and other side effects, is contraindicated in allergic, pregnant and lactating women, patients under 18 years of age. The use of the drug must be evaluated and directed by a physician, and any adverse reactions occurring after the use of the drug need to be promptly discontinued and treated by a physician.