Lupus erythematosus generally refers to systemic lupus erythematosus (SLE). The difference between SLE and vasculitis mainly lies in the definition of the disease, symptoms and prognosis. 1. Disease definition: SLE is an autoimmune disease that can invade joints, muscles and other organs and systems. Vasculitis is an autoimmune disease that mainly causes inflammation and necrosis of blood vessels. According to the size of affected blood vessels, it can be categorized into large vasculitis, medium-sized vasculitis and small vasculitis. 2. Symptoms: The common symptoms of SLE are rash, alopecia, mucosal ulcers, joint pain, muscle pain, etc. Vasculitis is characterized by skin rash, hair loss and muscle pain. While vasculitis is mainly characterized by rash, malaise, fever and other symptoms. 3. Prognosis: At present, the 10-year survival rate of SLE patients can reach 90% after active treatment. The prognosis of different types of vasculitis is different, in which patients with small arteries or micro-arteries of vital organs involved generally have poor prognosis and high mortality rate, while the prognosis of aortitis and giant cell arteritis is relatively good. If you are suffering from SLE or vasculitis, it is recommended that you go to the rheumatology and immunology department of a regular hospital and follow the doctor’s instructions.