There is no clear data on the percentage of hypertensive nephropathy developing into uremia. However, if hypertensive nephropathy is not actively controlled, the probability of developing into uremia is relatively high, and it is recommended to actively cooperate with the treatment. The progress of hypertensive nephropathy is relatively slow, the proportion of developing into uremia is not clear, there is no specific data, but should pay attention to the treatment. When hypertensive nephropathy patients develop uremia symptoms, the treatment mainly includes hemodialysis, peritoneal dialysis, and kidney transplantation. Uremia is an end-stage manifestation of renal failure and may be secondary to hypertensive renal damage. Due to the severe damage of renal units, the kidneys of uremia patients can not maintain their basic functions, causing systemic toxic symptoms, typical manifestations of itchy skin, edema, loss of appetite, fatigue, and so on, but also coagulation dysfunction, anemia, acidosis, renal bone disease and other complications. Patients with hypertensive nephropathy should pay attention to controlling blood pressure, keeping a good state of mind and regular physical examination in regular hospitals. Patients in the stage of uremia should actively seek treatment to avoid the accumulation of toxins in the body and complications.