There is no clear evidence that betaine is useful in the treatment of hyperuricemia. Betaine is a kind of alkaloid widely found in plants and animals, with a high content in beet sugar, which can be used to make hair conditioner, shampoo, hand sanitizer and other daily necessities, but there is no relevant experimental evidence to prove the existence of therapeutic effect of this substance on hyperuricemia. Hyperuricemia can be divided into primary hyperuricemia and secondary hyperuricemia, primary hyperuricemia is mainly due to diet, nucleic acid metabolism enhancement and other factors caused by excessive production of uric acid, while secondary hyperuricemia is secondary to kidney, blood and other systemic disorders, patients with hyperuricemia should be according to the specific type of disease for targeted medication and other treatments. It is recommended that patients with hyperuricemia go to endocrinology, rheumatology and immunology departments of regular hospitals for detailed consultation, and do not listen to prescriptions for self-medication.