The green brocade box and red iron box of Angong Niuhuang Pills are different packages of the same drug, probably from different manufacturers. Angong Niuhuang Pills is composed of ox horn, buffalo horn, artificial musk, pearl, cinnabar, andrographis paniculata, yellow rhubarb, scutellaria, gardenia, tulip jin, and icicle, etc. It has the efficacy of clearing away heat and detoxifying poison (removing heat, poison, and evil qi from the body), and subduing convulsions and opening up the orifices. Angong Niu Huang Wan can be used for fever, evil into the pericardium, high fever convulsions (due to high fever causing convulsions and seizures), delirium tremens (delirium, nonsense); stroke coma and encephalitis, meningitis, toxic encephalopathy, cerebral hemorrhage, septicemia, see the above symptoms. The adverse reactions and contraindications of Angong Niuhuang Wan are not clear, note that pregnant women should be cautious, athletes should be cautious. It is not yet clear the difference between the green brocade box and the red iron box of Angong Niuhuang Pills, which may only be the difference between the old and new packages, or different manufacturers, if you want to use Angong Niuhuang Pills, it is recommended that you ask your doctor for advice on how to use the medication.