Theoretically, the effect of tinidazole is better than metronidazole for the treatment of toothache. Metronidazole and tinidazole are both nitroimidazole drugs, but relatively speaking, metronidazole was developed relatively early and belongs to the first generation of nitroimidazole drugs. The second generation of nitroimidazoles was developed on the basis of metronidazole. Relatively speaking, the effect of tinidazole is stronger than metronidazole, and the side effects are smaller than metronidazole. However, the price of tinidazole is relatively more expensive than metronidazole, so patients can choose which anti-inflammatory drug to apply for tooth pain according to their own condition and financial situation. However, it should be noted here that taking anti-inflammatory drugs for tooth pain is not a cure, as anti-inflammatory drugs can only inhibit the growth of disease-causing bacteria, but it cannot completely remove the root cause of the disease, and it is recommended that patients with toothache go to a professional dentistry department for treatment of the cause of toothache.