Breast cancer neoadjuvant followed by surgical treatment is mainly to reduce the size of the tumor, reduce the difficulty of surgery and improve the rate of breast conservation. Breast cancer is a relatively common malignant tumor in clinic, and surgery is an important means to treat this disease. For patients with large lesions or those who are not suitable for breast preservation, the effect of pure surgical treatment is not ideal, and neoadjuvant chemotherapy before surgery can improve the prognosis as well as the cosmetic effect. Neoadjuvant chemotherapy can reduce the size of the lesion, and then surgery can reduce the difficulty of surgery, narrow the scope of surgery, and strive for breast-conserving surgery for patients who cannot breast-conserve, so as to achieve a better therapeutic effect, and also achieve a more desirable cosmetic effect. It is recommended that patients actively cooperate with the doctor’s treatment and maintain a good state of mind in order to prolong the survival period.