Pancreatitis combined with diabetic ketoacidosis requires rehydration therapy as well as symptomatic treatment, such as insulin to lower blood glucose, cefoperazone to fight infection, and surgical treatment. 1. Rehydration therapy: patients with pancreatitis combined with diabetic ketoacidosis at the same time, meaning that the condition is more serious, the need to assess the patient’s basic vital characteristics, in order to avoid accidents, and the need for rehydration therapy, but also need to test the same time, blood glucose and electrolytes, lowering blood glucose needs to be used in the use of insulin, but need to be injected. 2. Symptomatic treatment: for pancreatitis, the treatment needs to be based on the symptoms of pancreatitis, if the symptoms of edema, you need to accept the routine fasting, rehydration, as well as anti-infective treatment, such as the first choice of third-generation cephalosporins, ceftazidime or cefoperazone; if there are symptoms of pancreatic necrosis, you need to consider undergoing surgical treatment. In addition, the application of the above drugs have certain risks, patients need to get the guidance of specialists, not unauthorized use.