Deep coma is defined as the patient’s lack of response to any external stimuli and the generalized muscle relaxation without any voluntary movement. Coma is a kind of serious consciousness disorder, and deep coma patients usually have no response to any external stimuli, and the whole body muscle relaxation, without any voluntary movement. At the same time, deep coma patients have fixed eyes, dilated pupils, all kinds of reflexes disappeared, and urinary and fecal incontinence. The vital signs of patients in deep coma have obvious changes, such as irregular respiration, decreased blood pressure, and weak pulse. Clinically, large cerebral infarction, cerebral hemorrhage, craniocerebral trauma and carbon monoxide poisoning may lead to deep coma. If deep coma patients do not take timely treatment measures, the recovery of patients will be seriously affected. For deep coma patients, symptomatic supportive treatment, such as ventilator-assisted breathing and medication to maintain blood pressure, is the main focus. For deep coma patients, family members need to do a good job of daily care, such as turning over and knocking the back, massaging the limbs, etc., in order to promote local blood circulation, prevent the occurrence of pressure sores, pneumonia and other conditions, and standardized treatment under the guidance of a professional doctor.