Whether or not a person with hepatitis B virus can become pregnant is largely determined by whether or not the liver itself can withstand the burden of the entire pregnancy and delivery process. Currently, there are two tendencies that deserve attention: some people want to wait until the infectiousness of hepatitis B virus is reduced to zero or very low level before getting pregnant, which is not very realistic, and blindly waiting will miss the best time and age to get pregnant; the other part is to get pregnant without considering the body’s ability to bear it and with the mentality of trying it out, which is dangerous. Women with hepatitis B virus should have a serious and comprehensive medical checkup before planning to get pregnant to assess their physical status and figure out the severity of their disease so that they can choose the best time to get pregnant. If the patient is a virus carrier, the liver function series is always normal in long-term follow-up examinations, and the ultrasound examination does not suggest cirrhosis, pregnancy can be considered. If the patient is in the active stage of hepatitis B inflammation, with abnormal liver function check, self-conscious fatigue, loss of appetite and abdominal distension, pregnancy should be avoided at this time. Hard pregnancy in the active stage of liver inflammation increases the burden on the body, the liver has to accomplish more work, hepatitis is not easy to recover, but it can easily lead to heavy hepatitis and endanger the life of the pregnant woman. In addition, it is also not good for the development and growth of the fetus. Therefore, patients with active hepatitis B should first receive regular treatment, including antiviral and immunomodulatory therapy. It is beneficial for both mother and child to wait until the liver function is normalized and the viral replication index is negative or the replication capacity is reduced before pregnancy. For patients with active hepatitis, it is safer to get pregnant when the condition is stable and the liver function is normal for more than six months after treatment. If ultrasound examination reveals that hepatitis has developed to the level of cirrhosis, accompanied by significant thrombocytopenia, hypersplenism and coagulation disorders, it is better not to get pregnant. Patients with chronic hepatitis B with severe extrahepatic systemic manifestations, such as nephropathy and aplastic anemia, should preferably not become pregnant. Those who have had a history of pregnancy but terminated it because the liver could not tolerate it; preferably should not become pregnant. Those with hepatitis B virus infection with obstetrical and gynecological disorders who are not suitable for pregnancy, such as those with a history of repeat cesarean delivery are not suitable for pregnancy. It is best not to get pregnant. Current acute hepatitis B with significant liver function abnormalities is best to hold off pregnancy.