Acne is known as acne, and acne near the corners of the mouth may be related to the patient’s dietary habits, hormonal imbalance, infection by Propionibacterium acnes, and high oil secretion. 1. Dietary habits: If the patient often eats spicy and stimulating food, it is easy to cause acne near the corners of the mouth. Therefore, patients are advised to have a light diet and consume less spicy and stimulating foods, dairy products and sweets. 2. Hormone imbalance: When the level of androgen in the body is high, it can stimulate the development of sebaceous glands, thus stimulating the secretion of oil, which in turn induces acne. 3. Propionibacterium acnes infection: when the corners of the mouth are infected with Propionibacterium acnes, acne is also easy to produce, so patients should pay attention to the usual facial cleanliness. 4. Excessive oil secretion: The corners of the mouth belong to the T-zone of the face, where oil secretion is relatively vigorous, which can easily cause acne due to clogged pores. Therefore, patients can use oil-control cleansing products and skin care products. For patients with acne near the corners of the mouth, it is recommended to go to a regular hospital for examination and symptomatic treatment under the guidance of a professional doctor.