Lipoma is a western medical concept, Chinese medicine needs to recognize the evidence and prescribe a prescription, and is not limited to a specific prescription. In Chinese medicine, lipoma can be categorized into spleen deficiency, qi stagnation, phlegm condensation and phlegm turbidity coagulation, etc. It is suggested that patients should be treated according to different conditions. 1. Spleen deficiency and lack of transportation: Spleen deficiency and lack of transportation type lipoma often manifests as swelling under the skin, soft to touch, abdominal distension and loose stools (thin and unshaped feces), etc. It is suggested that patients can take prescriptions with the efficacy of benefiting qi and strengthening the spleen (regulating the qi of the spleen and stomach), and drying dampness and resolving phlegm (removing phlegm from the body by drying dampness), for instance, Six Gentlemen Soup and so on. 2. Qi stagnation and phlegm coagulation: If the patient is suffering from lipoma caused by Qi stagnation and phlegm coagulation, the symptom is often manifested as subcutaneous swelling or hard or soft, different sizes, weak pulse, etc. It is suggested that the patient can take the prescription with the effect of moving Qi and dispersing knots (to make the body’s qi smooth and dissolve the knots), dredging liver and strengthening the spleen under the guidance of the doctor, for instance, Free and Easy San. 3. Phlegm and turbidity cohesion: symptoms of phlegm and turbidity cohesion type lipoma often manifest as softness of subcutaneous swelling, white tongue, dizziness, etc. Patients can take prescriptions such as Phlegm Conducting Soup to play the role of phlegm-heat interlacing and dampness-heat transforming. If there is any malignant change in the patient’s condition, he should go to the hospital in time for consultation.