Uterine fibroids are the most common benign tumors of the female genitalia, commonly found in women aged 30-50. Usually, patients around 48 years old are in perimenopause and uterine fibroids 8cm can be divided into two cases of no treatment and treatment: a. No treatment Patients around 48 years old may not be treated if they have no obvious symptoms, and uterine fibroids can mostly shrink or symptoms disappear after menopause, and follow-up visits can be made once every 3-6 months. Second, treatment of patients with uterine fibroids 8cm, 20%-50% of patients with menstrual changes such as increased menstrual flow, prolonged periods, shortened cycles, irregular vaginal bleeding, as well as anemia, increased leucorrhea, lower abdominal pain, lumbago and other symptoms, at this time, treatment can be considered, there are two main treatment methods: 1, drug treatment: for patients with mild symptoms, near menopause or poor systemic symptoms, not suitable for surgery . Mifepristone can be used as preoperative medication or for early menopause, but after mifepristone antagonizes progesterone, the endometrium is stimulated by estrogen for a long time and the risk of lesions increases, so long-term use is not recommended; 2. Surgery: Patients who need to preserve fertility can undergo myomectomy, but there is a possibility of residual and recurrence after surgery. Patients without fertility requirements need to undergo cervical cytology before performing hysterectomy to exclude the possibility of combined endometrial cancer. If patients are intolerant or unwilling to undergo surgery, uterine artery embolization, high-energy focused ultrasound, and endometrial resection are feasible, but they are not the mainstream treatment options and have a certain possibility of residual and recurrence, and the results vary from person to person.