The hazards of coronary angiography on the body mainly include allergic reaction, kidney damage, puncture site damage, various complications of the heart, etc., but the probability of occurrence is relatively low, and the specific need for angiography needs to be assessed by clinicians. 1. Allergic reaction: the allergic reaction of coronary angiography is mainly due to the body’s allergy to the contrast agent. Currently, most of the contrast agents used for coronary angiography are iodine-containing contrast agents, which are more likely to trigger allergic reactions, so most of them need to do skin iodine allergy experiments before angiography, so as to avoid serious allergic reactions or even anaphylactic shock in the process of angiography. 2. Kidney damage: Kidney damage is most commonly caused by contrast medium, especially in older people with poor kidney foundation. The main manifestation is the sudden increase of blood creatinine after contrast. 3. Damage to the puncture site: Damage to the puncture site is also relatively common. During coronary angiography, it is necessary to insert the catheter by arterial puncture, and usually the artery to be punctured is the radial artery or the femoral artery. If the operation time is too long or the postoperative pressure is not proper, it may cause subcutaneous hematoma or arterial injury at the puncture site, or even arterial occlusion. 4. Cardiac complications: Cardiac complications usually occur in patients with severe coronary artery disease, which may include severe malignant arrhythmia, coronary artery rupture, entrapment, etc. Therefore, it is important to perform coronary angiography in order to minimize the risk of cardiac complications. Therefore, coronary angiography must strictly grasp the indications and operate in regular hospitals to avoid accidents.