A minor cold may affect the effectiveness of the HPV vaccine, and you should consider delaying the HPV vaccine after a cold. Colds are mostly viral infections, and the HPV vaccine is also a viral vaccine. There is a certain amount of interference between viruses, and the application of viral vaccines during a viral infection may affect the immune response and reduce the effectiveness of the immunization. Even for mild colds, the vaccine should not be applied during the onset of the disease. In addition, after viral infection, it is easy to have fever and other symptoms, which can be confused with the vaccine reaction such as fever produced after vaccination, affecting the judgment of vaccine reaction. Most vaccines, including the HPV vaccine, have a clear requirement to avoid injections when there is an acute infectious disease such as fever. Already have viral flu symptoms, need to promptly visit the fever clinic and treatment, after three days of healing, before considering the use of vaccines.