Ankylosing spondylitis is mainly symptomatic treatment, the onset of breastfeeding should be based on general treatment, physical therapy, if the symptoms can not be relieved, medication should be taken, but need to stop breastfeeding. 1. General treatment: breastfeeding women with ankylosing spondylitis should choose to sleep in a hard bed after the onset of the disease, take the supine position, avoid side bending. When standing, they should keep the posture of lifting the chest and closing the abdomen, which is conducive to the normal function of the spine. If physical strength allows, it is recommended to reasonable exercise, mainly aerobic exercise, such as walking. 2. Physiotherapy: you can usually choose heat therapy, such as hot bath or hot compresses, etc., which can promote local blood circulation, thereby relaxing the muscles, reducing pain, and facilitating the movement of the joints. 3. Medication: If the symptoms are severe, patients can take celecoxib, meloxicam and other non-steroidal anti-inflammatory drugs as prescribed by the doctor, which can improve the symptoms of low back pain, morning stiffness, joint swelling and pain. If NSAID treatment is ineffective, for patients with extra-articular symptoms, they can be treated with anti-tumor necrosis factor alpha antagonists such as etanercept and infliximab orally. The onset of ankylosing spondylitis during breastfeeding, it is recommended to go to the local regular hospital, under the guidance of the doctor to carry out relevant treatment.