There are many antiepileptic drugs, and there are already first-generation antiepileptic drugs, second-generation antiepileptic drugs and third-generation antiepileptic drugs. The first generation of antiepileptic drugs is relatively old, but there are still many commonly used drugs, such as carbamazepine, phenobarbital, phenytoin sodium, sodium valproate and so on. The two drugs, like ethosuximide and paracetamol, have less clinical application. There are also benzodiazepine sedative sleeping drugs, such as clonazepam, diazepam drugs, also in clinical application; 2, the second generation of anti-epileptic drugs: the traditional first generation of oral anti-epileptic drugs, such drugs on the basis of the original research and development, side effects are relatively smaller than the first generation, the role of epilepsy control is slightly better. At present, they include gabapentin, lamotrigine, levetiracetam, oxcarbazepine, pregabalin, topiramate, and non-amylate drugs; 3. Third-generation antiepileptic drugs: In recent years, new third-generation oral antiepileptic drugs have been developed, such as zonisamide, lacosamide, pirampanel, retigabine, parengabine, eslicarbazepine, lufenamide, bovacitam, and so on. However, most of the third-generation oral antiepileptic drugs have not yet been approved for marketing in China, and pirampanel is the only third-generation antiepileptic drug currently available. This drug belongs to AMPA receptor antagonist, compared to the second generation of drugs, the mechanism of action has reduced the incidence of adverse reactions and improved the tolerability of the drug, but there are not many clinical applications, and the long-term effects need further verification.