The eradication of gray nails cannot be guaranteed after nail removal. Since gray nails are a fungal infection of the nails, if the fungal infection is not completely removed, even if the diseased nails are removed, eradication cannot be achieved. You need to continue with topical antifungal medication after removing the nail. Nail plucking is a surgical procedure to remove the fungal infection from the nail, but currently it is not recommended for the treatment of gray nails. The nail plucking for gray nails is relatively painful, relatively damaging to the patient, and psychologically burdensome, adding additional fresh wounds that can easily lead to other bacterial infections and induce diseases such as onychomycosis and nail bed infection. Furthermore, after the nail is removed, the new nail will usually be smaller than the original nail, which can easily cause ingrown nails, which can affect the aesthetics and cause pain. The nail can be removed clinically with a knife or nail file, or the nail can be removed with a drug seal, and then treated with topical antifungal drugs, such as cyproheptadine and amorolfine, which can be used to reach the lesion and be more effective. If necessary, oral antifungal drugs such as terbinafine and itraconazole should be taken as prescribed by the doctor to remove the fungus in order to achieve the root cause.