The difference between a cheap cephalosporin and an expensive one may be in terms of manufacturer, specifications and may also be related to the generation of cephalosporin. Clinical cephalosporin includes more specific drugs, the same drug may be different due to different manufacturers, different specifications. Cephalosporins produced by foreign manufacturers, or those containing more active ingredients, may be more expensive. Secondly, third-generation cephalosporins may be slightly more expensive than first- and second-generation cephalosporins. The price depends on the specific case and cannot be generalized. Generally speaking, even if the price of the same drug is different, the efficacy is basically the same. It is recommended that patients follow the doctor’s instructions to choose the right drug for treatment, which is the most suitable to meet the condition, and has nothing to do with the price in general.