Since March, people’s concern about the domestic epidemic has become increasingly muted as the epidemic has continued to improve. When the epidemic first started making waves, people used to pick up their phones every day to check the latest news about the epidemic, but now life is gradually falling into place or the focus of attention on the epidemic is shifting to foreign countries. Recently, a piece of news has rekindled people’s concern about the epidemic, especially men. On March 12, Professor Li Yufeng’s team at the Center for Reproductive Medicine at Tongji Hospital of Huazhong University of Science and Technology said that there is a theoretical possibility of testicular damage caused by the new coronavirus, and therefore men of appropriate age who are infected with new coronavirus are advised to undergo fertility testing after recovery. New coronaviruses cause tissue damage by binding to host cell angiotensin-converting enzyme 2 (ACE2) through the stinger glycoprotein and thereby invading the cell. Importantly, many other organs of the body besides the lungs express ACE2, and the male testis expresses large amounts of ACE2 mainly in testicular spermatogonia, supporting cells and interstitial cells, all of which are relevant to male reproductive function. About the sequelae of New Coronary Pneumonia In an earlier report about the sequelae of New Coronary Pneumonia, experts have stated that mild cases do not leave sequelae and those who recover are not infectious. In contrast to the SARS treatment back then, the medical level was also very limited back then when SARS broke out, so some treatments with more side effects had to be used, so many SARS patients were left with varying degrees of sequelae. However, the current outbreak of Newcastle pneumonia was in the era of relatively advanced medical technology, and the means to deal with the virus were more mature. Except for a few severely ill patients, safer treatments were generally adopted, and sequelae were avoided as much as possible. In fact, although there have been an increasing number of cured cases in China, it is too early to talk about sequelae at this stage. This is because the assessment of sequelae from a medical point of view requires at least 6 months after cure to be more accurate. The latest reports of the new coronavirus affecting male fertility are only at the theoretical stage, and there is a real need for early attention and prevention. But there is another issue in life that concerns male fertility that many people do not pay attention to. Obesity affects fertility A study by the National Institute of Environmental Health Sciences shows that men with a high BMI have a much higher risk of infertility than men of normal weight, and obesity can lead to a variety of fertility problems in men, including erectile dysfunction and scrotal adiposity, all of which are obesity-derived co-morbidities. The scary thing is that obesity does not only affect reproductive function in men, but for women, polycystic ovary syndrome is also a key factor in many women’s infertility, making obesity a major obstacle to human reproduction. It is difficult to treat obesity complications with ordinary weight loss, and surgery can be tried if necessary. Among the many obesity complications, they all have one thing in common: the initial symptoms of the disease are not obvious and are difficult to detect, and as the degree of obesity becomes more serious, the related obesity complications also become more and more serious. Since the disease originates from obesity, weight loss has become an important means of treating obesity complications. However, due to the instability of the weight loss effect, it is difficult to ensure successful weight loss while the disease does not become more serious. In this case, weight loss metabolic surgery can solve this problem. Surgery can be tailored to the individual’s physique, and although the mechanism of weight loss is simply to achieve the effect of restricting food intake and reducing nutrient absorption, this process plays a significant role in the treatment of various diseases. In particular, the effectiveness of gastric bypass surgery for the treatment of obesity type 2 diabetes has been confirmed by most of the domestic and international literature as well as real cases. Therefore, infertility problems due to obesity can also be well treated by weight reduction surgery.