Positive WT1 gene indicates the presence of leukemia cells in the patient’s body, which may be due to the fact that the disease has not yet fully recovered or may be caused by relapse. It is necessary to further improve the flow cytology, chromosome and other tests, and then according to the results of the follow-up treatment. WT1 gene is a transcriptional regulator in the body with a dual role, which has an important role in the proliferation, differentiation, apoptosis and other processes of human hematopoietic cells. Clinical examination of WT1 gene can clarify the situation of patients in different periods, so as to understand the treatment and recovery of patients. Under normal circumstances, WT1 gene is negative, if positive test results indicate that the leukemia patient’s condition has not been cured or relapsed. patients with positive WT1 gene need to be analyzed in conjunction with other test results and physical conditions, such as whether there are infections, bleeding, etc., and at the same time, it is necessary to improve myeloid cytology, CT examination, etc., to determine the specific situation, and then take targeted treatment. Leukemia is mainly treated with chemotherapeutic drugs such as injectable vincristine sulfate, injectable cytarabine hydrochloride and other chemotherapeutic drugs, as well as targeted therapies, cellular immunotherapy and other modalities, which need to be determined in the light of the patient’s condition. WT1 gene test plays a very important role in the treatment and post-treatment, and it is recommended that you take regular examinations and take targeted treatments in a timely manner if abnormalities are found, so as to avoid delays in the disease. The WT1 gene test is an important tool in the treatment of WT1.