The chances of thick endometrium being cancerous after menopause are relatively not great, and after menopause, thick endometrium is not necessarily cancerous. After menopause, due to the gradual failure of ovarian function, the level of estrogen and progesterone in the body will decrease, which cannot maintain the growth of the endometrium, so that the thickness of the endometrium after menopause is usually less than 5mm. After menopause, if the thickness of the endometrium is more than 5mm, or if it is accompanied by irregular vaginal bleeding, it is mostly an abnormal phenomenon, which may be due to endometrial hyperplasia, endometrial polyps, endometrial cancer and other reasons. Therefore, you cannot judge the chance of cancer simply based on the postmenopausal endometrial thickening, and endometrial thickening can also be caused by benign lesions. For postmenopausal endometrial thickening, it is recommended to carry out hysteroscopy or adopt diagnostic scraping to take endometrial biopsy to clarify whether there is cancer or not, and then target treatment.