A 10-year-old girl of 3 months, with menarche, height 149 cm, bone age 12 years, no abnormal findings on pituitary MRI, was diagnosed by a local doctor as “central precocious puberty” and started to inject GnRHa 3.75 mg once every 28 days, and her menstruation stopped after 2 months. After half a year of application, the mother stopped the GnRHa treatment on her own for fear of side effects and switched to Chinese herbal medicine. After 3 months of taking the drug, her menses came back, and the mother was anxious about what to do. Let’s analyze, is this treatment good for the child? 1, The daughter was originally normal, optimistically predicted to grow up to 161cm lifetime height, without any disease, without any drug treatment. 2, When applying GnRHa, we must master the indications and regular application. Although on the whole, GnRHa is still relatively safe. The purpose of GnRHa application is to inhibit the hypothalamic-pituitary-gonadal axis, inhibit bone age, inhibit early menarche; early application can improve lifetime high, the course of treatment for at least 1.5-2 years. There will be an “ignition effect” at the beginning of the application, the gonadal axis will be inhibited in 3 months, and the progression of bone age will be inhibited in half a year; only the application of half a year is harmful but not beneficial. 3, Chinese medicine can not inhibit the true precocious puberty, especially the rapid progression of development. Many people think that Chinese medicine has no side effects, in fact, there is a misconception. Some Chinese medicines have excessive heavy metal content, and some Chinese medicines can cause liver and kidney damage when taken for a long time. Why take medicine if you are not sick? Such treatment is not at all beneficial to the child! If it is not true precocious puberty, such as girls’ breast development after the age of 8, bone age not advanced or first menstruation after the age of 10, height age in line with bone age, and disease factors (such as intracranial tumors, etc.) are excluded, there is no need for any drug treatment.