Calcium tablets do not usually cause premature epiphyseal closure. In general, whether or not the epiphysis closes is related to growth and development. If the body’s growth hormone, sex hormone and other hormones are secreted in large quantities in advance, or the normal structure of the epiphysis is damaged, the epiphysis may close prematurely. Calcium tablets generally have no significant effect on the epiphysis. However, it should be noted that excessive calcium ions in the body may cause hypercalcemia, kidney stones, etc., which will affect the absorption of other nutrients. In daily life, eat more protein-rich substances, pay attention to balanced nutrition, and at the same time carry out more whole-body exercise, ensure sleep time, generally can maintain the needs of growth and development. Drugs need to follow the doctor’s instructions for rational application.