Levofloxacin and cephalosporins are two different types of antibiotics, the specific which “good”, need to be based on the type of infected bacteria, the indications for treatment, whether there are contraindications and other comprehensive judgment. 1. Levofloxacin and other quinolone antibiotics (1) Indications: Used for the treatment of infections caused by sensitive bacteria in adults over 18 years of age, including pneumonitis, sinusitis, bronchitis, skin structure infections, prostatitis, pyelonephritis and other diseases caused by bacteria such as Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Streptococcus pneumoniae, Catamorium, and so on. (2) Contraindications: contraindicated in minors under 18 years of age; contraindicated during pregnancy and lactation; contraindicated in drug allergy. 2. Cephalosporin β-lactam antibiotics (1) Indications: cephalosporins are a huge variety of drugs, different kinds of drugs are sensitive to different bacteria, such as cefadroxil and other generation of Neisseria caused by infections have a good antibacterial effect. Cefoperazone and other three-generation cephalosporins on Escherichia coli, Klebsiella, Shigella, Haemophilus influenzae, Neisseria, etc. have good antibacterial effect, but can only be used in the presence of drug-resistant antibiotics ineffective. (2) Contraindications: nausea, vomiting, rash, shock, dizziness, convulsions and other symptoms need to stop using the drug immediately; penicillin, cephalosporins, allergy is prohibited. For the indications, to avoid the contraindications of the drug can achieve better therapeutic effects. No matter what kind of drug, you need to use the drug under the guidance of the clinician, prohibit unauthorized use of drugs.