Coronal groove rice-grain bumps are usually seen in pearly penile papules, glansitis or condyloma acuminata, and are usually associated with poor personal hygiene habits or high-risk sexual behavior. When the coronal groove is found to have rice grain bumps, it is recommended that the patient should go to the hospital in time to get a clear diagnosis and timely treatment to avoid the development of the disease and aggravation of the symptoms. 1, pearly penile papules: may be related to the foreskin is too long, foreskin coronal infection, and do not pay attention to local cleanliness and hygiene and other factors, can appear coronal groove rice grain bumps. Pearl-like penile papules are benign lesions that usually do not lead to dysfunction and therefore usually do not require special treatment. However, if there is localized redness and itching, a boric acid solution soaked in gauze can be applied wet. If bacterial infection is present in the affected area, topical mupirocin ointment can also be applied. In addition, liquid nitrogen freezing, laser treatment, etc., circumcision can be performed in patients with long foreskin; 2, glansitis: usually caused by pathogenic infection, foreskin is too long, urine stimulation, etc. are the causes, can lead to the existence of coronal groove rice grain bumps, often accompanied by redness, swelling, itching, pain and other discomfort. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. The bumps will gradually grow, coalesce and break down with the development of the disease. For this disease, patients can use medications such as imiquimod cream and ghost toxin ointment, as well as laser treatment, cryotherapy, and surgical excision.