Arms and shoulders will be uncomfortable, the possible causes are excessive fatigue, frozen shoulder, carpal tunnel syndrome, neurogenic cervical spondylosis, etc., generally not much to do with anxious and angry. 1. Excessive fatigue: It may be due to prolonged desk work, lifting heavy objects, or other strenuous exercise involving the upper limbs, etc., which will produce excessive fatigue of the muscles and tendons of the upper limbs, thus resulting in the phenomenon of discomfort in the arms and shoulders. 2. Frozen shoulder: Frozen shoulder may be caused by chronic inflammation and fibrosis of the joint capsule and surrounding ligamentous tissues, resulting in symptoms such as pain around the shoulder joint and limitation of activities, which may lead to arm and shoulder discomfort. 3. Carpal Tunnel Syndrome: Carpal Tunnel Syndrome is caused by increased pressure in the carpal tunnel, which stimulates the nerves and produces symptoms. Patients often feel numbness or pain in the thumb and middle finger, and in severe cases, the pain can reach the arm or even the shoulder. 4. Neurogenic cervical spondylosis: It may be caused by long-term strain injury of the cervical spine, herniated intervertebral discs, thickened ligaments and so on, resulting in irritation of the nerve roots, thus triggering neurogenic cervical spondylosis. Early symptoms include neck pain, stiffness, and radiating pain or numbness in the upper limbs, leading to discomfort in the arms and shoulders. There may be other reasons for arm and shoulder discomfort, so it is recommended to go to a regular hospital in time, complete the relevant examinations, clarify the cause of the disease, and then carry out targeted treatment or therapy under the guidance of the doctor.