Feasibility and safety analysis of laparoscopic partial nephrectomy with complete non-blocked renal artery OBJECTIVE: To investigate the safety, feasibility and clinical outcomes of a laparoscopic partial nephrectomy (LPN) with complete non-blocked renal artery. METHODS: From June 2014 to December 2014, we performed complete unblocked renal artery LPN in 6 patients. the mean age of the patients was 54.5 (38-79) years, including 4 males and 2 females. The median body mass index of the patients was 26.6 (23.4-31.2) kg/m2. 4 tumors were on the right side and 2 on the left side in this group. The tumor R.E.N.A.L. score was 4.3 (4-5), and the mean tumor diameter was 2.8 (1.5-4.8) cm. intraoperatively, before resection of the tumor, the normal renal parenchyma at the edge of the tumor resection was pre-sutured with barbed sutures with appropriate force to lift the renal tissue to control bleeding. The tumor was removed cold with scissors between the tumor and the pre-stitched suture. A trabecular renal parenchymal suture is performed when the partial nephrectomy wound bleeds, and this operation is repeated until complete removal of the tumor. Finally, the renal trabecular suture was completed. RESULTS: In this group, four cases were completed by the transabdominal route and two cases were completed by the retroperitoneal route. All patients did not block the renal artery, with an average intraoperative bleeding of 60.8 (20-150) ml and an average operative time of 106.7 (65-130) min. There were no perioperative transfusions or serious complications. The average postoperative hospital stay was 4.3 (2-6) d. Postoperative pathology was clear cell carcinoma in four cases, complex renal cyst in one case, and vascular smooth muscle lipoma in one case, and all surgical margins were negative. CONCLUSION: Complete unblocked renal artery LPN is a safe and effective technique in selected patients and this technique protects renal function by avoiding the duration of renal thermal ischemia. Figure-1: Pre-sutured normal renal parenchyma at tumor margin Figure-2: Cold excision of tumor with scissors Figure-3: Sutured wound with barbed sutures