Breast milk jaundice 21mg/dl is hyperbilirubinemia in newborns due to breastfeeding. A bilirubin of 21mg/dl at this time can indicate a risk of bilirubin encephalopathy. Breastmilk jaundice is jaundice in breastfed newborns that persists for 3 months after birth and is characterized by increased unconjugated bilirubinemia. Jaundice appears after 1 week of life and peaks around 2 weeks. If breastfeeding is continued, the jaundice may continue for 4 to 12 weeks. When the total bilirubin is more than 20mg/dl, it can cross the blood-brain barrier and cause damage to the central nervous system. Breastfeeding should be stopped and blood exchange therapy should be carried out promptly. If breastfeeding jaundice occurs, go to the hospital and follow the doctor’s advice.